Web20 dic 2024 · In the epigenetics field, large-scale functional genomics datasets of ever-increasing size and complexity have been produced using experimental techniques … WebHere, we introduce Juicer, an open-source tool for analyzing terabase-scale Hi-C datasets. Juicer allows users without a computational background to transform raw sequence data into normalized ...
Fob1-dependent condensin recruitment and loop extrusion on …
Web10 apr 2024 · The scientific method used to examine chromatin in a cell is called single-cell Hi-C. But the data produced is lacking, limiting the ability of researchers to clearly determine how the cell behaves. Chen will study how to improve the experimental quality of this data, as well as build tools to better study the datasets. WebHi-C Datasets, genomic coordinates of human/mouse pooled domains/boundaries, cell-specific domains/boundaries; mmc3.xlsx - Table S2. Depletion/Enrichment Analysis. "C" … halfords bank holiday opening times 2022
essHi-C: essential component analysis of Hi-C matrices
Web13 dic 2024 · The output compartment score reflects the chance of a genomic window being in the A compartment. The implemented tool, namely CscoreTool, is ∼30 times faster … Web20 apr 2024 · The sequencing depth also affects the relative level of variability observed in Hi-C datasets. The coefficient of variation (CV) at fixed genomic distance, C V (i) = σ (i) / μ (i), is a value that at high-enough read coverages reflects the biological variability and locus-specific biases (Muller et al., 2024). Web3 feb 2024 · Inspired by early Hi-C results, revealing the correspondence between Hi-C data and a fractal globule conformation of the chromosome , we developed the notion of nestedness. Critically nestedness, or the notion that structural hierarchy in the chromosome is driven by the tendency of smaller clusters to be nested within larger clusters, … halfords barnstaple phone number