Panama diethylene glycol disaster
WebAccording to the agency, the most recent incident occurred in Panama in September 2006 and involved DEG-contaminated glycerin used in cough syrup, which resulted in dozens of hospitalizations for serious injury and >40 deaths. In late 1995 and early 1996, ≥80 children died in Haiti owing to DEG-contaminated glycerin in acetaminophen syrup. WebMar 2, 2024 · Singh J, Dutta AK, Khare S, et al. Diethylene glycol poisoning in Gurgaon, India, 1998. Bull World Health Organ 2001;79:88–95. PMID:11242827; CDC. Fatalities associated with ingestion of diethylene glycol-contaminated glycerin used to manufacture acetaminophen syrup—Haiti, November 1995–June 1996. MMWR Morb Mortal Wkly Rep …
Panama diethylene glycol disaster
Did you know?
WebApr 20, 2024 · Diethylene glycol, or DEG, is a chemical that can cause potentially fatal kidney and neurological toxicity. Researchers have implicated the chemical in multiple … WebDiethylene glycol (DEG) is an organic compound with the formula (HOCH 2 CH 2) 2 O. It is a colorless, practically odorless, and hygroscopic liquid with a sweetish taste. It is a four carbon dimer of ethylene glycol.It is miscible in water, alcohol, ether, acetone, and ethylene glycol. DEG is a widely used solvent. It can be a contaminant in consumer products; this …
WebOct 24, 2006 · Clinical symptoms of diethylene glycol include vomiting, altered sensorium, oliguria, azotaemia and raised transaminase levels. All our patients had anuria and encephalopathy. Encephalopathy followed development of acute renal failure by 3–5 days and was fatal in majority of cases. WebApr 1, 1998 · A comment on this article appears in "Haitian diethylene glycol disaster and Dante's darkwood." JAMA. 1998 Sep 16;280(11):965. A comment on this article appears in "The Haitian diethylene glycol poisoning tragedy: a dark wood revisited." JAMA. 1998 Apr 15;279(15):1215-6.
WebMay 17, 2024 · The lakes also provide water for much of Panama’s growing population. Image. A cargo ship on Gatún Lake as it transited the Panama Canal in April. Lower … WebSulfanilamide (diethylene glycol) disaster—United States, 1937. Alan D. Woolf, in History of Modern Clinical Toxicology, 2024. ... and cerebrospinal fluid frozen and archived from …
WebLittle was known about diethylene glycol toxicity at the time, and many cases of acute kidney failure and death occurred. 40 To avoid similar tragedies in the future, animal drug testing was mandated by the Food, Drug, and Cosmetic Act of 1938. 132 Unfortunately, diethylene glycol continues to be sporadically used in other countries as a ...
Webrecent mass poisoning, in the Republic of Panama in 2006, where diethylene glycol (DEG) was discovered in a sugarless expectorant preparation. DEG was used in the product in place of pharmaceu-tical grade glycerin (a safe and commonly used diluent in pharmaceutical formulations) because it had been mislabeled. margini cosa sonoWebAug 1, 2024 · In the case of elixir sulfanilamide, diethylene glycol (DEG) was the culpable toxic substance. DEG is and was a chemical used in antifreeze. In this tragedy, the S. E. Massengill Company used diethylene glycol as an excipient in elixir sulfanilamide. cupcone dessertWebJan 1, 2024 · Again, in Panama in September 2006, a physician noticed an unusual cluster of cases of acute renal failure. A case-control study identified an erroneous substitution … cupco trading incWebStudy objective: Diethylene glycol is a toxic industrial solvent responsible for more than 13 mass poisonings since 1937. Little is known about the clinical spectrum, progression, and neurotoxic potential of diethylene glycol-associated disease because of its high mortality and the absence of detailed information in published mass poisoning reports. margini cssWebFind many great new & used options and get the best deals for 1985 Press Photo Two Bottles of Austrian Wine with Diethylene Glycol Ingredient at the best online prices at eBay! Free shipping for many products! margini del conto economicoWeb二甘醇對人類及動物均具毒性，如攝取過量，可損害 肝臟 和 腎臟 ，嚴重者可引致死亡。 中毒初期可出現 嘔吐 、 腹瀉 及腹痛，情況嚴重者在其後數天可出現急性 腎衰竭 及其它症狀。 人體的二甘醇致死劑量約為每公斤體重1毫升，不過有報告指兒童口服5毫升、成人口服20毫升已可致命。 它的毒性來自人體攝入後，會代謝為腎毒性極強的 草酸 ，導致急性 腎衰 … margini delle zolleWebOct 17, 2006 · From 1995 to 1996, 89 children lost their lives in Haiti, after taking acetaminophen in which the sweet syrup base contained diethylene glycol. In 1998, 33 children in India died after being given medicines containing the industrial solvent. In Panama, investigators are trying to determine how the diethylene glycol reached the … margini del cuore