Web8 Mar 2024 · THBS1 is a marker of high-grade glioma. a Immunohistochemistry (IHC) of THBS1 in patient samples from grade II astrocytomas and oligodendrogliomas (upper … Web17 Nov 2016 · This study attempted to uncover the signaling pathway of MSC proliferation. Under low-oxygen culture conditions, MSCs maintained their proliferation and differentiation abilities for a long term. The Notch2 receptor was up-regulated in MSCs under hypoxic conditions. Notch2-knockdown (Notch2-KD) MSCs lost their cellular proliferation ability …
Notch2 Signaling Regulates the Proliferation of Murine Bone …
Web21 Jun 2024 · Thbs1 is a biomarker for NAFLD in humans, and pharmacological and genetic approaches for the modulation of Thbs1 activity may have the therapeutic potential for treating hepatic steatosis. Fund A full list of funding bodies that contributed to this study can be found in the Funding Sources section. Keywords Thrombospondin 1 CD36 Hepatic … Web31 Oct 2006 · Note: Secreted by thrombin-activated platelets and binds to the cell surface in the presence of extracellular Ca 2+ (PubMed:6777381, PubMed:101549).Incorporated into the extracellular matrix (ECM) of fibroblasts (PubMed:6341993). The C-terminal region in trimeric form is required for retention in the ECM (PubMed:18285447). Also detected in … pathé vaise avatar
Frontiers Intraperitoneally Delivered Mesenchymal Stem Cells
Web18 Sep 2013 · Mice deficient in thrombospondin (TSP)-1 ( thbs1−/− ), an extracellular matrix glycoprotein that bridges cell–cell interactions, are prone to lipopolysaccharide-induced lung injury and show... Web21 Apr 2024 · Tight regulation of positive and negative regulators of angiogenesis is essential, particularly in the eye where their dysregulation can lead to vision loss. Thrombospondin-1 (TSP1) is a matricellular protein that negatively regulates angiogenesis and inflammation in the eye. It aids ocular vascular homeostasis such that its loss … pathé vaise film